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What are the Side Effects of Glucosamine and Chondroitin?

Though currently widely-used for as effective arthritis supplement, there are some side effects of glucosamine and chondroitin that you have to know about.

Glucosamine and chondroitin have both been proven to be safe and effective in relieving pain and inflammation associated with arthritis.

Benefits of Chondroitin Glucosamine Supplements

A number of glucosamine chondroitin study have revealed the effect of these components in the body. Glucosamine helps make your cartilage stronger and rigid. It is also proven to relieve pain and treat osteoarthritis in the joints. Chondroitin, on the other hand, enhances the shock-absorbing capacity of the cartilage and makes it more flexible. It has also been seen to lessen the inflammation and promote improved joint function in general.

Glucosamine, Chondroitin Sulphate with MSM

Majority of arthritis supplements contain glucosamine and chondroitin sulphate, along with MSM (methylsulfonylmethane). This is believed to be the best chondroitin and glucosamine form as it is seen to be most effective. Aside from the glucosamine chondroitin benefits mentioned, taking those with MSM has promising added health benefits which include inhibiting pain, lessening inflammation and reducing muscle spasms or joint pains.

The typical recommended glucosamine and chondroitin dosage ranges from 1,200 to 1,500 milligrams per day. Supplements in 400 mg forms can be taken thrice a day, while 600 mg tablets can be taken twice a day for a span of about two months.

Side Effects of Glucosamine and Chondroitin

There are a few side effects of glucosamine and chondroitin that has been seen in a few cases. Some of the glucosamine chondroitin msm side effects include:

  • Nausea
  • Diarrhea or Constipation
  • Indigestion
  • Upset stomach
  • Soft stools
  • Heart burn
  • Build-up of pressure when applied on the eye

The main problem with chondroitin and glucosamine supplements is that they are unregulated. Thus, when you buy glucosamine chondroitin tablets or capsules, you have to take extra caution. Some manufacturers are not as reliable as some, so make sure that you only choose the best.

Glucosamine Chondroitin Creams and Liquid

Recently, there are now liquid as well as glucosamine chondroitin cream that are being sold. Creams are applied topically; camphor and menthol are also added for added effectivity for pain relief. However, there has not been a conclusive study to determine whether they work as effectively as orally taken supplements.

An Alternative to Regular Chondroitin Supplements

Though chondroitin supplements mostly work, there are a few times when they do not work for some people. There are also cases wherein arthritis is too severe that ordinary supplements based on these two do not suffice. If you have been taking them for about a month, yet experience no amount of relief, or if you have been taking it and are discomforted by the side effects, it would be high time for you to look into other options.

Our Recommendation

Luckily, XtendLife has extended its product range and have introduced Not Just Joints (formerly Arthrit-Eze) as its own version of arthritis supplement. It contains natural ingredients that have been seen to be equally effective in relieving pain and discomfort caused by arthritis. Ingredients include Cetyl Myristoleate, Phellodendron Bark, Celery Extract as well as SAMe.

It is proven safe to take and ensures no negative side effects. If you want to avoid the possible side effects of glucosamine and chondroitin but at the same time enjoy their arthritis pain relieving benefits, Not Just Joints (formerly Arthrit-Eze) is surely the best supplement there is for you.


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Not Just Joints combines 31 key ingredients to form an advanced formula never before achieved.

It is an all-in-one complementary formula, allowing you to reduce the number of separate supplements and other medications taken.